Inexpensive DIY MtF HRT

I began MtF HRT in 1989, had SRS in 1999. Injectable estradiol valerate and transdermal estradiol don't affect liver and blood clotting at all, but transdermals are much more expensive. When I was on factory-made injectable estradiol valerate, I developed an allergy to some impurity in it. Because of that, I began to compound injectable estradiol valerate for myself by myself at home: I mix estradiol valerate powder, a preservative (antibacterial) and a solvent (all pharmaceutical quality, from pharmaceutical trade companies) in multi-dose vials, add Castor oil from a pharmacy or less viscous ethyl oleate 99.9% (you can choose) and sterilize sealed vials. After I tested on myself, in 2006 I began to sell to other MtF. In October 2017 I began to ship worldwide.

I sell ready-to-use vials with estradiol valerate solution 400 mg/vial (10 ml/vial 40 mg/ml) sterilized at 126úC for 60 USD/vial, 2 to 8 vials per purchase, currently expiration December 2023. Shipping 5-8 USD depending on country. For example, shipping to USA 7 USD, delivery with USPS registered mail, tracked. Every my packet was successfully received (to USA in 20, 12, 16, 11, 11, 13, 14, 16, 14, 10, 8, 7, 12, 7, 9, 15, 13, 9, 10, 8, 10, 11, 10, 8, 8, 10, 11, 14, 14, 18, 21, 25, 20, 8, 26, 21, 18, 28, 15, 16, 18, 22, 23, 18, 19, 20, 21, 33, 26, 22, 18, 26, 26, 19, 18, 18, 28, 20, 21, 18, 15, 13, 12, 16, 11, 16, 20, 19, 21, 13, 14, 16, 12, 21, 23, 12, 12, 22, 14, 13, 16, 16, 16, 13, 11, 37 days).

If you haven't a preferred dosage then I usually advise to MtF 7 mg (0.18 ml) every 5 days, each vial for 9 months. This dosage gives average blood estradiol level as from oral estradiol about 20 mg/day, but is much less expensive, 35 times less expensive than the cheapest estradiol pills in InHousePharmacy. This dosage is enough high to suppress testosterone production by testicles completely without antiandrogens. 7 USD/month for safe highly effective MtF HRT.

You may wonder why so cheap - no, it's estradiol in pharmacies what's orverpriced. Cost of estradiol is less than 1% of pharmacy prices for pills. Also, only 5% of oral (swallowed) estradiol reaches blood. In other words, injected estradiol is 20 times more effective than swallowed. Don't worry, I do make a profit.

You can inject with insulin syringes (1 ml or less) with inbuilt (non-detachable) needles 1/2" - 5/8" (12-16 mm) long into deltoid muscle.

About safety: I use terminal heat sterilization: I heat already mixed solution in sealed vials in water boiling in a pressure cooker under pressure +20 PSI at temperature 126úC (overkill - more than recommended 121úC) for 30 min. Bacteria, fungi, viruses cannot survive that. Bureaucrats get their salary for inventing new rules, no matter how unreasonable. I was accused that I don't follow rules for American compounding pharmacies like special workspace with controlled airflow and 0.2 micron filtering. However, the accuser doesn't want to think that chemical factories sell hormone powders non-sterilized. What's the sense to use controlled airflow and filtering if one of ingredients is not sterile, and filtering doesn't stop viruses? Anyway terminal sterilization must be used, and I do use it. Any efforts before terminal sterilization are pointless because the powder is not sterile, I sterilize everything as the final stage. If you want me to sterilize at even higher temperature then email me about it.

If you want, instead of vials with ready-to-use solution I can send you vials with estradiol valerate powder 400 mg/vial for 40 USD/vial, a vial with a solvent, a vial with a preservative and detailed instructions how to mix them and sterilize.

I offer also ready-to-use solution of estradiol enanthate (shortly EEn to distinguish it from ethinylestradiol - EE) 500 mg/vial (10 ml/vial 50 mg/ml) in ethyl oleate for 80 USD/vial. Estradiol enanthate is longer-acting than estradiol valerate. Currently I advise 0.22 ml weekly, but you can try longer time between injections, up to 2 weeks.

Another option is ready-to-use solution of estradiol valerate 50 mg and progesterone 250 mg, 12 USD/vial, 8 to 16 vials per packet. Custom EV/P ratio is possible, or EV + hydroxyprogesterone caproate.

Ask me any questions via email, specify the country you are living in (shipping fee and payment options depend on country).